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However, given the prevalence of the MTHFR variants in the general population and from which the laboratory reference values for Hcy are determined, any value near the upper limit of normal may be cause for concern

Protein-containing media used in Plasmodium cultures has been hypothesized to contribute to the absence of PS exposure induction, through sequestration of the eryptosis-inducing compound (Bobbala et al., 2010a), and human plasma has been suggested to contain pro-survival factors protecting against eryptosis induction (Walsh et al., 2002)

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For systemic, compounded, or procedure-adjacent workflows, clinics should review the full medication list, supplements, allergies, wound-care products, and relevant laboratory concerns