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Also, nicotine significantly induces vascular smooth muscle cells proliferation via the upregulation of bFGF mitogen and several MMPs, which leads to an augmentation of lesions and development of intimal hyperplasia, atherosclerosis, and aneurysm

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[16] Keys has stated that her parents never had a relationship, and her father was not in her life

Additionally, some studies suggest that vaping may also cause damage to the DNA in sperm and this can also affect the chances of a healthy pregnancy

Our case series serves to highlight the non-specific nature of syphilis-related oral manifestations