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R This pathway is the primary defense against: Aflatoxin B1 (a carcinogenic mycotoxin produced by Aspergillus) Cadmium Epoxides (reactive Phase I intermediates from polycyclic aromatic hydrocarbons) Lipid peroxidation products (4-hydroxynonenal, malondialdehyde) Mercury (organic and inorganic forms) Reactive oxygen species (ROS) and reactive nitrogen species (RNS) GSTs exist in three locations: cytosolic (the largest class, with alpha, mu, pi, theta, sigma, omega, and zeta subfamilies), mitochondrial (kappa class), and microsomal (MAPEG family)

It doesnt rely on getting your heart racing to burn calories

10.1038/nrc3205 Nat

The IL-6/HO-1/STAT3 signaling pathway is implicated in the amelioration of acetaminophen-induced hepatic toxicity: A neonatal rat model

Research domains include obesity, metabolic regulation, and combination incretin-based therapies