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Their study, published in JAMA Network Open on April 25, 2025, reveals that the states with historically high smoking rates have seen the most dramatic declines

Cigarette smoke exposure in Gpr15 -deficient mice attenuates TNBS-induced colitis but exacerbates DSS-induced UC colitis To investigate the role of Gpr15 in UC and CD under cigarette smoke exposure, we used Gpr15- deficient ( Gpr15 / ) and Gpr15 +/+ wild-type (WT) mice

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