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The state's history of tobacco farming has contributed to a cultural norm where smoking is more widely accepted and less stigmatized

In a "clarification" published this week in the Federal Register , the Food and Drug Administration indicates that e-cigarettes cannot legally be sold as tools to quit smoking unless their manufacturers go through the prohibitively expensive process of getting them approved as new pharmaceutical products

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The stained cells were acquired and analyzed using a BD FACSAria III flow cytometer (Becton Dickinson, Franklin Lakes, NJ, USA) and data were analysed with Flow Jo software 53