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An important observation in this study was that the quantities of all the mentioned MMPs were greatly increased in the presence of both keratinocytes and fibroblasts, showing the importance of the crosstalk between keratinocytes and fibroblasts in MMP production, and thus the relevance of a bilayer skin model

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Readings should be made at 20 min for urticaria or anaphylaxis-like immediate adverse drug reactions from betalactam antibiotics, neomycin, gentamycin, bacitracin, diclofenac

Rathi R, Rathi B