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[57] The activation of nAChRs by nicotine boosts the release of neurotransmitters, while altering the function of some of themsuch as norepinephrine, dopamine, serotonin (5-HT), and endogenous opioid peptidesthus modifying the action of the peripheral nervous system and causing cigarette addiction

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1 Smoking drastically reduces male and female fertility because smoking harms the genetic make-up in eggs and sperm, which can make conception difficult

2000;106(4):E47

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