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The graphic designs used on cigarette packages in some countries are indeed grotesque, featuring images such as blackened and cancerous lungs, rotten teeth, and patients in hospital beds on ventilators

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Table 2: Number of MACE cases, Hazard Ratio and Rate Difference in a Meta-Analysis of 15 Clinical Trials Comparing CHANTIX to Placebo* The meta-analysis showed that exposure to CHANTIX resulted in a hazard ratio for MACE of 1.95 (95% confidence interval from 0.79 to 4.82) for patients up to 30 days after treatment