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The film itself was a box office dud, earning just $37.7m in the US on a budget of $70m

Metabolites of a tobacco-specific lung carcinogen in the urine of nonsmoking women exposed to environmental tobacco smoke in their homes

On his 1962 album "The Button-Down Mind on TV," Newhart delivered "Introducing Tobacco to Civilization," a satirical and absurd anti-smoking monologue imagining English explorer Sir Walter Raleigh shipping tobacco from North America to Europe and explaining how to use it

Many users will tell you that the emissions from electronic cigarettes are harmless water vapour and there is, therefore, no need to ban the use of these devices indoors

As more research points to sugars role in reinforcing nicotines effects and increasing toxic byproducts in smoke, the need for greater public awareness becomes more urgent