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4-HNE has been implicated in cancer and inflammatory diseases owing to its ability to form 4-HNE-protein adducts that can impair cell signaling and alter gene expression [83, 103, 112]

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11 Laboratory data and several case series involving analysis of bronchoalveolar lavage fluid samples from patients who presented with significant respiratory compromise showed that vitamin E acetate, an additive in some THC-containing vaping products, was strongly linked to the EVALI outbreak

Quick Terminology Check: In Scandinavia, the word snus is often used loosely, but two different products matter here

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