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While promising, evidence is limited to preclinical data with no registered clinical trials to date, and thus human efficacy and safety remain to be established

Amylin analogs like cagrilintide work through the area postrema and nucleus tractus solitarius in the brainstem, a region that processes satiety signals through a completely separate neuronal network

Plasma oxalate as a predictor of kidney function decline in a primary hyperoxaluria cohort

Salvianolic acid B protects human endothelial progenitor cells against oxidative stress-mediated dysfunction by modulating Akt/mTOR/4EBP1, p38 MAPK/ATF2, and ERK1/2 signaling pathways

Preconditioning with soluble guanylatecyclase activation prevents postischemic inflammation and reduces nitrate tolerance in heme oxygenase-1 knockout mice