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GPX4 converts glutathione (GSH) to oxidized glutathione (GSSG) and converts lipid peroxides to the corresponding alcohols, thus preventing the occurrence of Fenton reactions and subsequently inhibiting ROS generation (Liu Y

Thus, this potential difference in the relationship between mitochondrial function and other variables can complicate the fitting of the SEM model if data from both those with and without NDR are included in the same model for several reasons

The chemical structures of flavonoids classify them into several subgroups, including flavones, flavanones, flavanols, isoflavones, the leucoanthocyanidins, anthocyanins, and chalcones (129)

[DOI] [PMC free article] [PubMed] [Google Scholar] 64.Tracy BL, et al

Liraglutide, semaglutide and tirzepatide have been shown to reduce major cardiovascular events, and similar trials are ongoing for other investigational incretins