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Extracellular vesicle-based nucleic acid delivery

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705 Albiflorin not only inhibits neuronal ferroptosis by reducing the levels of lipid peroxide and iron and regulating ferroptosis-related proteins, but also inhibits microglia activation and reduces the production of pro-inflammatory cytokines, thereby promoting motor function recovery after SCI in rats

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The central pro-inflammatory cytokines, IL-1, TNF and IFN, have been shown to inhibit -cell function and activate apoptotic pathways in -cell lines, human islets, and rodent models (34, 44)