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The patch should be placed every day when the patient gets up and should be removed on the same day when the patient goes to bed in the case of the 16-hour patch, or on the following day when the patient gets up in the case of the 24-hour release patch.31,37 The site used for the patch should be changed every day in order to prevent the appearance of erythema and pruriginous exanthema

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If you are also weighing non-nicotine alternatives, our guide to the best nicotine-free vapes covers the zero-nicotine side of that decision