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DAO, Mast Cells and Undermethylation Histamine symptoms may come from food-derived histamine, impaired DAO activity, histamine intolerance, or a high whole-blood histamine pattern associated with undermethylation

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Theo Haradis has done where mast cells and microglia also mediate the fear pathways, change the limbic system, change the amygdala literally our perception of what is a threat in the world is distorted