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GIP has been shown to decrease food intake while blunting the metabolic adaptive responses that usually occur with calorie restriction resulting in weight reductions, and when combined with GLP-1 receptor agonism, may result in greater effects on markers of metabolic dysregulation such as body weight, glucose and lipids

Thinner individuals may require shorter needles, while those with more muscle or adipose tissue may need longer ones to reach the muscle layer effectively

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