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For example, patients carrying high-risk alleles of HLA-DRB1 may require more aggressive monitoring and early treatment to prevent the exacerbation of joint damage

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Materials and methods Study subjects Research subjects From August 2016 to August 2019, children with RMPP were recruited from the Department of Pediatrics at The First Peoples Hospital in Zhengzhou, China, According to the diagnostic criteria of RMPP [3]: (1) the fever persisted, and clinical symptoms deteriorated after seven days of anti-infective therapy with macrolides

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Vitamin Cor ascorbic acidwhen used intravenously in pharmacological amounts acts as a pro-oxidant and increases the production of hydrogen peroxide, which represents one significant potential mechanism of action of vitamin C