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Accordingly, we are proposing that in calculating the relative weight for MS-DRG 018 for FY 2024, only those claims that group to MS-DRG 018 that (1) contain ICD-10-CM diagnosis code Z00.6 and do not include payer-only code ZC or (2) contain condition code ZB (or, for subsequent fiscal years, condition code 90) would be excluded from the calculation of the average cost for MS-DRG 018

2010 Apr;15(2):85-94

210 Chauvel, V., Multon, S

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The LR3 extension does not make it "safer" -- it makes it longer-acting and less regulated by binding proteins, which from a risk standpoint means sustained free IGF-1R activation without the IGFBP buffering system that modulates native IGF-1 activity in healthy physiology