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It restricts oxygen, weakens the lungs, slows muscle recovery and drains energy

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Constipation can be severe and lead to an increased risk of intestinal obstruction and ileus (MHRA warning 2017 Clozapine: reminder of potentially fatal risk of intestinal obstruction, faecal impaction, and paralytic ileus )

Study profile: the Japan society and new tobacco internet survey (JASTIS): A longitudinal internet cohort study of heat-not-burn tobacco products, electronic cigarettes, and conventional tobacco products in Japan