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The longitudinal study had a high risk of bias 17 , and three of the six cross-sectional studies 14,19,23 and the case report 15 had a moderate risk of bias

Additionally, cardboard provides a physical barrier that helps to shield cigarettes from moisture, heat, and light, helping to maintain their freshness and quality from the point of manufacture to the end consumer

Despite this intensive puffing schedule, first-generation users absorbed only a very small amount of nicotine (boost of 2.8 ng/ml)

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The start of the GFN conference saw the European premiere of a documentary A Billion Lives which is the WHO estimate of tobacco-related deaths by 2100