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Disperse the fuel (the most important step): shake the lighter up and down 4-6 times (shake once after each filling is completed) 5

Editor: Michael Cummings, Medical University of South Carolina, UNITED STATES Received: March 22, 2019

BTI acquired Reynolds in 2017, and is working to integrate the operations, while also realizing the synergies expected from the deal

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Future YPEL5-dependent small-molecule degraders could be developed to enable a multimeric neosubstrate to engage two substrate-binding modules with enhanced avidity 40