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Consequently, concurrent administration of hepatotoxic medications that are metabolised via these pathways may result in elevated concentrations of the concomitant drug, which can potentially culminate in hepatic injury

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In this study, 31% and 53% of subjects with measurable cotinine and nicotine levels did not report exposure, suggesting that efforts by the smokers lobby to categorize current legislation as exaggerated or overreaching may be misguided or unfounded