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An IQOS approval could also send a strong signal to consumers that these products are likely to be less harmful for them to use, said University of Waterloo tobacco expert David Hammond, and in practice, that will serve as an endorsement.

While smokers reportedly exhibit increased EV release and altered EV cargo profiles in the lungs 44 , the degree to which smoking or E-cigarette use can alter the release and/or functionality of EVs derived from BC cells remains unknown

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