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Cigarette smoke-induced autophagy has also been shown to cause degradation of ciliary proteins, and to promotes MUC5AC expression through activation of c-Jun N-terminal kinase (JNK) and activating protein (AP)-1 (175, 176)

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Directed by horror-leaning UK filmmaker James Watkins ( Eden Lake , Speak No Evil ), Clayface is based on the eponymous Batman comic book villain, and follows a rising actor (Tom Rhys Harries) who turns to radical surgery when he is disfigured by a vicious mobster

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