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On the flip side, it is also considering the fact that the addition of such flavors to e-cigarettes may help regular smokers to switch to less harmful tobacco products

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relatively large apparent volume of distribution of ~2-3 L/kg in horse, cows, sheep & dogs reflecting its relatively high lipid solubility in dogs, xylazine is metabolized by the liver to ~20 metabolites, with only 8% eliminated unchanged in the urine, (Rector et al, 1996