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Therefore, there must be common endogenous mechanisms beyond and outside of the mentioned systems: dopamine, serotonin, glutamate, GABA, adrenergic/noradrenergic system, acetylcholine, and NO-systems

Lesion volume was expressed as a percentage of the contralateral hemisphere volume [1]

% MPE (% maximal possible effect) = (control group flinch number of times - experimental group flinch number of times) 100 / control group flinch number of times Statistical analysis was carried out by one-way analysis of variance (ANOVA) with a post hoc test

Bournia VK, Fragoulis GE, Mitrou P, et al (2021) All-cause mortality in systemic rheumatic diseases under treatment compared with the general population, 20152019

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