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Studies in our review did not provide dietary data for us to determine if diet-related byproducts or metabolites directly or indirectly impacted by smoking affect the structure and function of the oral microbiome

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One-way ANOVA and Kruskal-Wallis tests were used to compare continuous variables across groups, with post hoc Tukeys HSD test or Dunns pairwise test with Bonferroni correction applied to significant ANOVA results to determine inter-group differences

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