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The observed increase in TCR diversity, including longer and more diverse CDR3 regions, is consistent with antigen-driven T cell activation, though it does not pinpoint specific antigenic triggers

Overall, our results suggest that higher levels of education in society are associated with increased awareness of the complications and diseases related to smoking, as well as the economic burden it imposes, which may lead to decreased smoking or smoking cessation

The standard 20-cigarette pack is often the most economical option for the majority of consumers, especially considering pricing and taxes

The Marlboro brand has been under pressure from competitors and lower-priced cigarette brands amide economic uncertainty and high unemployment

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