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Smoking affects local anesthesia through several mechanisms: Studies indicate that smokers may experience up to 40% shorter duration of local anesthetic effectiveness, often requiring additional doses during procedures

IQOS and Heated Tobacco: No Exceptions Heated tobacco devices (like IQOS) are treated exactly the same as electronic cigarettes

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Evaluation of tobacco product marketing authorizations of new/novel products (e.g., PMTA, MRTPA), such as potential impact on health outcomes and effects on tobacco use/behavioral outcomes, including patterns of use among users (e.g., dual use vs

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