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Another study using an air-liquid interface (ALI) to assess the cytotoxic effects on human bronchial epithelial cells, showed that IQOS exposure induced higher cytotoxicity (reduced metabolic activity) than e-cigarettes or air controls but lower than combustible cigarettes 22

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The review of these applications is of the utmost public health importance, and we do not make decisions lightlywe must make sure final decisions issued on these applications are appropriate on both the scientific merits and the law. As noted in recent testimony to the Health Subcommittee of the House Committee on Energy and Commerce, the Center for Tobacco products has received nearly 27 million applications for new tobacco products

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