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Although schools were purposively stratified by gender composition to maximise diversity, selection relied on local gatekeepers, which may have introduced recruitment bias despite efforts to include staff and pupils of different ages, backgrounds, and smoking exposures
Tobacco smoke contains many chemicals in a cigarette that are harmful to both smokers and non-smokers and at least 69 of these can cause Cancers, such as lung, oesophagus, larynx, mouth, throat, kidney, bladder, liver, pancreas, stomach, cervix, colon, and rectum, as well as acute myeloid leukaemia

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