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That matters for anyone whose gut doesnt absorb B12 well, think pernicious anemia, celiac disease, or a history of gastric surgery

Pyridoxal phosphate (PLP) is integral to one-carbon metabolism, a series of biochemical reactions necessary for the synthesis of nucleotides and other molecules essential for DNA and RNA production (57, 58)

Untreated Vitamin B12 deficiency can lead to severe anemia, nerve damage, cognitive decline, and irreversible neurological impairment

So that's definitely that woman

Yes, preclinical studies show it can repair the intestinal lining, reduce inflammation, and normalize gut motility core issues in IBS