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Despite our sample being approximately sixfold smaller than the British GWAS 16 , we robustly replicate their findings that the UGT2B10 locus on chromosome 4 is associated with N -desmethylclozapine serum concentration, and hence the CLZ-to- N -desmethylclozapine metabolic ratio

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Both organizations also consider tobacco prices and taxes to be the most important factors in controlling tobacco use