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Blend into the rest of face and neck

Consistency: Most studies delivered treatment multiple times per week for several weeks

Accumulating evidence indicates that Vitamin D exerts its anti-inflammatory effect in part by inducing MAPK phosphatase-1 (MKP-1), thereby suppressing p38 MAPK activation and inhibiting the production of pro-inflammatory cytokines such as IL-6 and TNF- in monocytes [202]

PMCID: PMC7037223 Khavinson VKh, Kuznik BI, Tarnovskaia SI, Lin'kova NS