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[DOI] [PMC free article] [PubMed] [Google Scholar] Kraus D, Yang Q, Kong D, Banks AS, Zhang L, Rodgers JT, et al
Administering doses higher than natural levels may increase the risk of mortality
Their weakness is the mirror image: a molecule that reshapes a cell in a dish may do nothing useful in an injured brain
The shared host-cell adhesion and haem-binding functionality of many NTHi proteins suggests that bacterial haem-utilisation plays an important role in its interplay with host epithelial cells and may provide an adaptive advantage for colonisation in environments with low haem-iron availability ( 4.2 Survivability and virulence in the respiratory tract Continued NTHi survival in the respiratory tract requires a secure source of host-derived haem
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