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Current research indicates that the cell cycle arrest depends on the activity of cyclin-dependent kinase inhibitors (CDK) p16 and p21, often regulated by the main tumor suppressor protein p53, whose elevated level is frequently used as a marker of senescence detection [21]

Parenteral administration is often used to treat Vitamin B12 deficiency

Martyn Hooper, in his book, explains in simple terms the function of the ileum: "The intrinsic factor produced in the stomach makes its way, with food that is being digested, through the small intestine

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