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Mechanistically, it appears plausible that exposure to tobacco smoke can skew immune responses by impairing Th1-type and augmenting Th2-dependent responses, mainly by altering the immune functions of a variety of immune cells and aggravating the allergic inflammation and sensitization [3,11,12,13,14,15,16,17,18,19]

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While the Federal Aviation Administration doesn't publish the details about most of its in-flight smoking fines, only about 10% of the fines issued by the FAA are related to in-flight smoking, according to an analysis by USA Today

see section VI.D)

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