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Moreover, the combination of osimertinib and navitoclax (an inhibitor of BCL-2 that could increase apoptosis and reduce chemo-resistance) was feasible in patients with EGFR -mutated NSCLC in a phase IB trial ( NCT02520778 (first posted: 13 August 2015) ) ( 148)

Never smokers consuming 4+ drinks also had elevated risk for these cancers (HR = 2.3, CI = 1.2 4.3)

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Acknowledgments We extend our gratitude to Rachel Visontay for their contributions in meticulously editing the journal article

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