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Indeed, the neuroprotective effects of nicotine in PD have been examined in vitro and in vivo, and are hypothesized to be primarily due to its pro-survival effects on dopaminergic neurons (56)

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Likewise, Juel (2008) used data from 1997-2001 to calculate that nearly all the difference in male life expectancy between Denmark and Sweden and about three-quarters of the difference in female life expectancy could be attributed to smoking- and alcohol-related deaths