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Black hairy tongue can appear brown, yellow, or green, as well as black, according to the NIH, depending on the bacteria and fungi that can overgrow on the altered surface, as well as other anaerobic bacteria that ferment food particles trapped in the papillae
We used macrophages in this study because they are a secondary target of HIV-1 infection and a major viral reservoir where it is difficult to effectively suppress the virus with antiretroviral agents 39,40
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