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Retaining nicotine at pleasurable or addictive levels while reducing the more toxic components of tobacco is another general strategy for harm reduction (for a recent review of this issue, see Russell, in Ferrence et al., 2000)

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The placenta and umbilical cord are the most important organs connecting the mother and the fetus: being responsible for transporting nutrients and oxygen, and timely discharging the fetal metabolic waste (19)

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