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The data showed altered expression levels of genes after exposure to IQOS and Glo (115 genes and 2 genes, respectively) compared to thousands of perturbations with CS exposure (2809 genes)

One could replace "the use of tobacco" in the above definition with a range of behaviors from "brushing teeth in the morning" through "looking right and then left when crossing the street" to "saying 'bless you' when someone sneezes." By this criterion, then, humans have lost autonomy over most of their routine behaviors, which renders the criterion so non-specific that it loses any utility as a marker of addiction

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3) Vape Pens A vape pen provides more control and adjustable features for the vaper than a cigalike or disposable, but can end up being more expensive and time-consuming