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Moreover, in order to clarify the previously proposed methodological problems of abstainers misclassification, sick quitter hypothesis, and potentially confounding factors 17 , we categorized drinking status of ex-drinkers into regular drinker to avoid misclassifying the former drinkers as abstainers and controlled 15 confounders to minimize confounding

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Treatment recommendation based on the individual prevention concept It is critical to assess the individual patient risk profile prior to treatment

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