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Cigarette smoking, meanwhile, became a mass-market phenomenon in the 20th century, linked to convenience, stress relief, and social habits

Respiratory system: Smoking tobacco products, such as cigarettes, can severely damage the respiratory system

doi:10.1007/s40257-020-00547-7

Furthermore, NNALa metabolite formed after 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) enters the body and a well known carcinogenurinary levels increased markedly after hookah use, indicating the presence of tobacco-specific nitrosamines in hookah smoke [63, 82]

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