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Regular alcohol intake, certain prescription medications, thyroid disease, and pernicious anemia an autoimmune condition affecting B12 absorption are also recognized factors

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Vitamin B12 is a critical factor in the methylation cycle

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Thyroid C-Cell Tumors: In mice and rats, tirzepatide (the active ingredient in Zepbound and Mounjaro) caused an increase in thyroid C-cell tumors, including medullary thyroid carcinoma (MTC)

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Series 2: 3-AR knock-out mice (the gene for the 3 receptor is knocked out) in the same design, to check whether 3 is necessary for the AOD-9604 effect

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47 Most studies in patients on HD have shown benefits of B12 either on its own or extra benefit when added to other B vitamins (mostly folate)

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