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Remarkably, GH-responsive neurons are widely distributed across numerous brain areas, including the hippocampus, bed nucleus of the stria terminalis (BNST), amygdala, cerebral cortex, cerebellum, specific thalamic regions, and several brainstem nuclei (8, 9, 12)

A subsequent larger RCT (n=72) confirmed these findings, showing improvements in gait speed, grip strength, exercise capacity, waist circumference, and systolic blood pressure (Kumar et al., J Gerontol A Biol Sci Med Sci, 2023) [21]

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SARM1 The targeting of enzymes that deplete NAD + has demonstrated therapeutic potential in fatty liver disease

The temperature of the testicle increases and may lead to decreases in spermatogenesis as well as testosterone production [13]