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These findings were further confirmed by treatment of HDAC6 inhibitor tubacin to PC-12 cells over-expressing human mutant (A53T) -synuclein (-syn) and SH-SY5Y cells with MPP (+) that led to defects in aggresome formation accompanied by massive cell death in response to misfolded protein-induced stress (Su et al., 2011)

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Each modality does what the other cannot." For users who want to layer modalities, the Evenskyn Lumo+ (the brand's RF-EMS-LED handset) serves as the natural pairing partner

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