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The post-synaptic currents, which were recorded in the presence of strychnine, picrotoxin and tetrodotoxin, represented spontaneous bursts likely mediated by AMPA receptors

doi:10.1101/cshperspect.a009183 Acknowledgments This work was supported by the Chang Gung Memorial Hospital [Grants CMRPD1A0531, CMRPD1C0231, CMRPG391311, CMRPG3A1131] and the Ministry of Science and Technology, Taiwan [Grant NMRPD181001-3]

Despite the lack of a lasting effect on food intake, cagrilintide elicited a sustained and noteworthy reduction in body weight in WT mice (day 21 body weight loss: 3.4 g or 66% vs WT Veh