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Anyone with significant medical conditions, anyone pregnant or breastfeeding, and anyone on multiple medications needs a careful review first not because problems are expected, but because limited human data means we don't assume

Women typically start with 50mg daily and may progress to 75mg if well-tolerated

The NNMT-blocking mechanism of 5-amino-1MQ has been shown to increase levels of the cofactor NAD+, whose replenishment in organisms promotes muscular, cognitive, and immune function, as well as increased lifespan [4, 5]

Where neurological symptoms are present, loading runs 1mg on alternate days until there is no further improvement, which is a presentation that belongs with a GP or specialist rather than a wellness clinic

The response to vitamin B12 injections can vary based on individual needs and deficiencies