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Cells were incubated with QIs or parent compounds for 2.5 h, based on the time-dependency of QIs-induced loss of cell viability (Supplementary Figure S3)

Ezatiostat leads to JNK activation by inhibiting GSTP1

Genes that were upregulated by more than 1.4-fold in response to GSTO1 knockdown showed an enrichment of pathway terms related to lipid synthesis, sterol metabolism and transcriptional repression

Warning: Consult a healthcare professional before using this product if you are trying to conceive, pregnant, or lactating, under the age of 18, or have a medical condition